Amazing Spider-Man #228

Murder By Spider!
At the beginning of the issue, Spider-Man was irresistibly drawn to a secluded mansion, where the reclusive old man living within died the following day, seemingly attacked by masses of spiders. Further investigations led him to an exquisite apartment building, where a second victim turned up. When the signal that drew Spider-Man to the mansion turned up again, the web-slinger was drawn to the source - a maniacal scientist bent on cashing his talents to control the arthropods.